University of Cambridge | United Kingdom
Our aim is to study the structure and function of multi-component assemblies and better understand how they participate in fundamental cellular processes. We are exploring bacterial multi-enzyme assemblies involved in RNA turnover, processing, and non-coding RNA function. We have also been studying the structure and mechanism of multi-enzyme assemblies from central metabolism and bacterial machineries which transport proteins and small molecules across membranes.
Keywords: Structure & function / macromolecular assemblies / X-ray crystallography / cryoEM / molecular biophysics / RNA turnover & processing / riboregulation / membrane transport