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EMBO Member

Federica Sallusto

Institute for Research in Biomedicine, Bellinzona | Switzerland

EMBO 2011

T cells in immunity and autoimmunity

We combine ex vivo analysis of memory T lymphocytes with in vitro priming experiments to understand the mechanisms that control T cell commitment to different fates and the co-regulation of effector functions and migratory capacities. In parallel, we use the mouse system to address fundamental questions in the regulation of lymphocyte trafficking in immunity and autoimmunity.

Keywords: T lymphocytes / cytokines / immunological memory / lymphocyte migration / chemokine receptors

Subject area(s): Immunology

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