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EMBO Young Investigator

Halyna R. Shcherbata

MPI für biophysikalische Chemie, Göttingen | Germany

YIP 2015

Biological roles for miRNAs in stress and disease

We aim to understand biological roles of miRNAs under normal, stress, and disease conditions, using Drosophila as a model system for conserved mechanisms underlying human disorders. Based on our findings, we believe that miRNAs act as (i) temporal codes for cell differentiation; (ii) canalization factors against transcriptional noise; (iii) stress and disease response elements; and (iv) intermediaries between different signaling pathways.

Keywords: microRNA / Drosophila / muscular dystrophy / stem cells and their niches / cell signaling and differentiation

Subject area(s): Development | RNA | Signal Transduction

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