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EMBO Member

Maria Dominguez

Instituto de Neurociencias, Alicante | Spain

EMBO 2007

Mechanisms of growth control and cancer

The impressive precision of organ size and shape and the bilateral symmetric growth of similar anatomical parts reflects the robustness of genetic programmes that control growth as well as the developmental plasticity necessary to counteract variations arising from morphogenetic and genetic errors, injury, or other external perturbations. We investigate the genes, mechanisms, and the brain circuits behind this control and how these genes are rewired to instigate tumour initiation and progression.

Keywords: Developmental plasticity / insulin / growth control / symmetric growth / cancer / Drosophila

Subject area(s): Signal Transduction | Signal Transduction | Molecular Medicine | Differentiation & Death | Development | Chromatin & Transcription | Signal Transduction | Molecular Medicine | Development | Signal Transduction | Molecular Medicine | Development | Signal Transduction | Molecular Medicine | Development | Development | Molecular Medicine | Signal Transduction | Signal Transduction | Molecular Medicine | Development | Signal Transduction | Molecular Medicine | Development | Signal Transduction | Molecular Medicine | Development | Signal Transduction | Molecular Medicine | Development | Molecular Medicine | Development | Signal Transduction | Molecular Medicine | Development

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