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EMBO Member

Matthew Freeman

University of Oxford | United Kingdom

EMBO 1999 | SciSocC 01–04 | WisC 10–13

Intramembrane proteases in intercellular signalling

My group discovered the rhomboid family of intramembrane proteases as the principal regulators of EGF receptor signalling in Drosophila. More recently the group has focused on the mechanism and function of rhomboids and rhomboid-like proteins in a wide range of species.

Keywords: Drosophila / intercellular signalling / growth factors / development / proteases

Subject area(s): Development | Proteins & Biochemistry | Signal Transduction

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