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EMBO Associate Member

Scott Emr

Cornell University, Ithaca | United States

EMBO 2008

Endocytic trafficking and the and ESCRT complexes

Our research focuses on three topics: (1) the genetics of endocytic trafficking and receptor down-regulation; (2) genetic and biochemical analysis of phosphoinositide lipid- and ubiquitin-dependent membrane sorting and signaling pathways and (3) defining the pathways for maintaining the composition and quality of membrane proteins both at the plasma membrane and the lysosomal membrane (nutrient transporters, channels, receptors, etc.).

Keywords: Membrane trafficking / protein sorting / vesicles / phosphoinositide lipid signalling / multivesicular body

Subject area(s): Membranes & Transport | Microbiology, Virology & Pathogens | Signal Transduction

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