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EMBO Young Investigator

Mads Gyrd-Hansen

Ludwig Institute for Cancer Research, Oxford | United Kingdom

YIP 2015

Ubiquitin signalling in innate immunity

We study molecular mechanisms governing signal transduction during innate immune responses. Through this, we aim to understand the molecular switches that on one hand protect against pathogens, but that also contribute to chronic inflammation, autoimmunity, and development and progression of cancer. A central focus of the lab is to elucidate the role and regulation of ubiquitin modifications in these processes.

Keywords: Ubiquitin / signalling / pattern recognition receptors / inflammation / cancer

Subject area(s): Immunology | Molecular Medicine | Signal Transduction