EMBO Young Investigator
Ludwig Institute for Cancer Research, Oxford | United Kingdom
We study molecular mechanisms governing signal transduction during innate immune responses. Through this, we aim to understand the molecular switches that on one hand protect against pathogens, but that also contribute to chronic inflammation, autoimmunity, and development and progression of cancer. A central focus of the lab is to elucidate the role and regulation of ubiquitin modifications in these processes.
Keywords: Ubiquitin / signalling / pattern recognition receptors / inflammation / cancer