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EMBO Young Investigator

Philip Zegerman

Gurdon Institute, Cambridge | United Kingdom

YIP 2015

DNA replication initiation control in eukaryotes

To successfully pass on their genetic information, every organism must make a perfect duplicate of their genome in every cell cycle. As a result, the process of DNA replication must be strictly regulated, within the normal cell cycle, after DNA damage and during development. Our research aims to understand the molecular mechanism of how this strict regulation of DNA replication is achieved.

Keywords: DNA replication / CDK / checkpoint / cell cycle

Subject area(s): Cell Cycle | Genome Stability & Dynamics