Cell morphogenesis
We use fission yeast and Drosophila embryos as model systems to study how cell type-specific architecture is set up and maintained, in order to provide either robust or dynamic cell shape and consequently cell type-specific function. For this we study the plethora of roles exerted by the actin and microtubule cytoskeletons, which together with associated proteins are the main organisers of cellular content.
Keywords
Tissue morphogenesis / cell architecture / cell polarisation / cytoskeleton organisation / cell force generation