Biological energy transduction processes
My research is centred on energy transduction in mammalian mitochondria, especially the structure, mechanism, regulation and assembly of the ATP synthase complex. Those interests extend to bacterial ATP synthases, and how they differ from the human enzyme, so as to develop new drugs to inhibit the bacterial enzymes selectively.
Keywords
Mitochondria / energy transduction / ATP synthase / rotary mechanism / regulation / proteomics of mitochondria