Francis Crick Institute, London | United Kingdom
EMBO 2004 | Council 15–17
Karen's own research focuses on the tumour suppressor protein p53, which plays an important role in cancer prevention. Her lab is interested in understanding the signals that induce p53 and the functions of p53 that contribute to its ability to prevent cancer progression. This work has also expanded to encompass an interest in cancer metabolism. Ultimately, they hope to be able find ways to this research for cancer therapy.
Keywords: Tumour suppressor genes / cell cycle / apoptosis / p53 / cancer metabolism