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EMBO Associate Member

Michael R. Green

University of Massachusetts, Worcester | United States

EMBO 2010

Eukaryotic gene regulation and cancer biology

My lab studies the mechanisms that regulate eukaryotic gene expression, and the role of gene expression in cancer development. To pursue these interests we use transcription-based approaches and functional screens to identify new genes and regulatory pathways involved in cancer. These studies are intended to enhance our understanding of how normal cells become cancerous and reveal potential new targets for therapeutic intervention.

Keywords: Apoptosis / cancer biology / gene regulation / genome-wide RNAi screening / pre-mRNA splicing

Subject area(s): Chromatin & Transcription | Molecular Medicine | RNA

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