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EMBO Member

Shankar Balasubramanian

University of Cambridge | United Kingdom

EMBO 2012

Chemical biology of the genome

Our lab work on the chemical biology of the genome. One major area of investigation is the structure, function and manipulation of non-canonical DNA and RNA structures in nature, which is largely focused on our exploration of four-stranded DNA and RNA G-quadruplex structures. The other area that my group has recently started working on concerns the existence an function of chemically modified bases in the genome.

Keywords: Nucleic acids / sequencing / G-quadruplexes / chemical biology

Subject area(s): Genomic & Computational Biology | Molecular Medicine | RNA

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