Institut de la Vision, Paris | France
We primarily study the mechanisms which control the development of neuronal connectivity with a special interest in commissural projections. We try to understand how axon guidance mechanisms have evolved. We also investigate the role of axon guidance molecules in retinal neo-angiogenesis, myelination and axonal regeneration. Our group has recently developed novel tissue clearing and 3D imaging techniques to study human embryogenesis.
Keywords: Axon guidance / nervous system development / netrin / slit / embryogenesis / tissue clearing / evolution
Subject area(s): Cell & Tissue Architecture | Development | Neuroscience