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EMBO Member

Alain Chédotal

Institut de la Vision, Paris | France

EMBO 2019

Axon guidance mechanisms

We primarily study the mechanisms which control the development of neuronal connectivity with a special interest in commissural projections. We try to understand how axon guidance mechanisms have evolved. We also investigate the role of axon guidance molecules in retinal neo-angiogenesis, myelination and axonal regeneration. Our group has recently developed novel tissue clearing and 3D imaging techniques to study human embryogenesis.

Keywords: Axon guidance / nervous system development / netrin / slit / embryogenesis / tissue clearing / evolution

Subject area(s): Cell & Tissue Architecture | Development | Neuroscience