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EMBO Young Investigator

Alan Cheung

University, Bristol | United Kingdom

YIP 2019–2023

Molecular mechanisms of gene transcription.

My goal is to understand the interplay between transcription factors, Pol II and chromatin coactivator complexes, and uncover fundamental molecular mechanisms of transcription and its regulation. My lab uses a multi-disciplinary approach encompassing crystallography, cryo-electron microscopy, biochemistry, biophysics and genetics to study the large macromolecular machines required for gene transcription.

Keywords: Coactivator / transcription / chromatin / structural biology / genome biology / histone modifications / epigenetics

Subject area(s): Chromatin & Transcription | Proteins & Biochemistry | Structural Biology & Biophysics