EMBO Young Investigator
Institute of Cancer Research, London | United Kingdom
My laboratory is focussed on RNA polymerase III gene transcription and its regulation. Using integrated structural biology techniques with functional genome-wide studies in living cells, we are particularly interested in understanding the role of RNA polymerase III in cancer. We are also interested in mechanistically understanding the role of the interspersed RNA polymerase III loci and associated factors in shaping the eukaryotic genome.
Keywords: Gene transcription / RNA polymerase III / tRNAs / genome organisation / cancer
Subject area(s): Chromatin & Transcription | Proteins & Biochemistry | Structural Biology & Biophysics