EMBL, Heidelberg | Germany
Our group studies time and timing in development and how oscillatory signalling dynamics control spatiotemporal pattern formation. Key questions include how environmental and metabolic cues are integrated with signalling dynamics and linked to developmental robustness and plasticity. We use vertebrate segmentation (mouse, medaka) as main experimental model, providing a striking example of collective, emergent oscillations and synchronization to investigate time, space and information.
Keywords: Collective oscillations / signaling / pattern formation / scaling / dynamical systems / theoretical biology / developmental plasticity / self-organization