EMBO Member
Alexander Stark
EMBO 2015
Former EMBO Young Investigator (2013)
Research Institute of Molecular Pathology (IMP), Vienna, Austria
Understanding gene regulatory DNA sequences.
The regulation of gene expression is a crucial process in all organisms. While the DNA sequence of cis-regulatory elements (enhancers) encodes the regulatory information needed to specify gene expression patterns, the requirements for enhancer activity remain unknown. We use bioinformatics and molecular biology to decipher gene regulatory sequences and study the proteins that cells employ to regulate gene expression.
Keywords
Regulatory genomics / transcriptional regulation / enhancers / CRMs / computational biology / transcription factor cofactors