
EMBO Associate Member
Alfredo Oscar Cáceres
EMBO 2018
INIMEC-CONICET-Universidad Nacional Córdoba (AR), Córdoba, Argentina
Cytoskeletal signaling and neuronal polarity
My lab works on the mechanisms underlying the development and maintenance of neuronal polarity. We initially focused on the involvement of microtubules in axon-dendrite formation, and more recently on kinesin-like proteins, actin regulatory proteins and factors (GEFs and GAPs) modulating the activity of small Rho-GTPases. We use a variety of cell biological techniques including live-cell imaging and super-resolution microscopy.
Keywords
Neurons / polarity / axons / dendrites / cytoskeleton / trafficking / Rho GTPase signalling