Goethe University, Frankfurt | Germany
EMBO 2015 | EEsC 18–20
We are interested in elucidating the molecular pathways involved in the crosstalk between vessels and nerves and how signalling integration at the neurovascular interface is achieved. We focus on the role of vessels during the development of the nervous system, in the adulthood during synaptic plasticity and cognition and in pathology during tumour invasion and metastasis. We use both mouse and zebrafish models for our research.
Keywords: Neurovascular interface / neuronal development / neuronal plasticity / angiogenesis / tumour growth