EMBO Member
Anastassis Perrakis
EMBO 2023
Former EMBO Young Investigator (2001)
Netherlands Cancer Institute, Amsterdam, Netherlands
Integrative structural cell biology and biophysics
Our lab on one hand develops computational methods for constructing experimental and computational atomic models of proteins, developing new ideas, tools and resources for the community (e.g. PDB-REDO, AlphaFill). Concurrently, we study the structure and interactions of macromolecules involved in lysophosphatidic acid signalling and maintain a network of collaborations that focuses on the role of microtubule interactions to modulate cellular function.
Keywords
Structural biology / X-ray crystallography / tubulin detyrosination / spindle assembly checkpoint / autotaxin / AlphaFill / PDB-REDO