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EMBO Young Investigator

Andrea Pauli

IMP, Vienna | Austria

YIP 2019

Molecular control of the egg-to-embryo transition

My lab is interested in the mechanisms that initiate life of sexually reproducing organisms. What is the molecular basis of fertilization? How is the cytoplasm of the egg remodeled into the cytoplasm of an embryonic cell? And what is the contribution of largely neglected small proteins? We combine genetic studies in zebrafish and medaka with biochemistry, cell biology, live-cell imaging and genomics to study these fundamental questions.

Keywords: Fertilization / translation / small proteins / maternal-zygotic control / ribosome / zebrafish

Subject area(s): Development | Proteins & Biochemistry | RNA

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