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EMBO Member

Andreas Trumpp

DKFZ, Heidelberg | Germany

EMBO 2011

Stem cells and cancer

Our goal is to elucidate the molecular and cellular basis of hematopoietic stem cell self-renewal and differentiation as well as to characterize the complex dynamic interactions within the stem cell-niche unit. In addition, we have established a program to functionally characterize cancer and metastasis stem cells at various levels and translate these findings into novel diagnostic and therapeutic tools to detect and target metastatic disease.

Keywords: Stem cells / self-renewal / cancer & metastasis / circulating tumor cells / targeted therapy

Subject area(s): Development | Molecular Medicine | Signal Transduction