Stem cells and cancer
Our goal is to elucidate the molecular and cellular basis of hematopoietic stem cell self-renewal and differentiation as well as to characterize the complex dynamic interactions within the stem cell-niche unit. In addition, we have established a program to functionally characterize cancer and metastasis stem cells at various levels and translate these findings into novel diagnostic and therapeutic tools to detect and target metastatic disease.
Keywords
Stem cells / self-renewal / cancer & metastasis / circulating tumor cells / targeted therapy