Search    Show all

1 People found

filters applied:


1 / 1

EMBO Member

Angela Krämer


EMBO 1995 | FelC 03–06

RNA targets and partners of splicing factors

Pre-mRNA splicing is essential for gene expression and plays a major role in proteomic and functional complexity. Our research focused on human RNA-binding proteins coordinating splice site recognition. With high-throughput methods we identified RNA binding sites of splicing factors and studied protein-protein interactions to understand the biochemical mechanisms that control splice site definition and alternative splice site decisions.

Keywords: Pre-mRNA splicing / alternative splicing / RNA binding proteins / protein-protein interactions / snRNP biogenesis

Subject area(s): Proteins & Biochemistry | RNA