Search    Show all

1 People found

filters applied:


1 / 1

EMBO Member

Anna Bigas

IMIM, Barcelona | Spain

EMBO 2014

Stem cell specification and leukemia development

The research activity in our laboratory is focused on understanding the molecular mechanisms that regulate stem cell commitment, maintenance, differentiation and oncogenic transformation, mainly focussed in the hematopoietic system. We are currently using genetic mouse models to decipher how pathways such as Notch, Wnt or NFkB are involved in these biological processes.

Keywords: Hematopoiesis / stem cells / Notch / T-ALL / NF-kappaB / Wnt

Subject area(s): Development | Molecular Medicine | Signal Transduction