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EMBO Member

Anna Philpott

University of Cambridge, Cambridge | United Kingdom

EMBO 2020

Coordination of proliferation and differentiation

I aim to characterise mechanisms that control the ability of cells to respond to cell fate challenges, as well as explore mechanisms that co-ordinate cell cycling with stem cell maintenance and differentiation during development and reprogramming, using both mammalian systems and Xenopus tadpoles. I am also investigating how cell cycle and differentiation are perturbed in cancer, with the aim of developing novel differentiation therapies.

Keywords: Cell differentiation / cell cycle / cyclin dependent kinases / bHLH transcription factors / phospho-regulation

Subject area(s): Cell Cycle | Chromatin & Transcription | Development | Differentiation & Death