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EMBO Member

Anne Bertolotti

MRC LMB, Cambridge | United Kingdom

EMBO 2013

Misfolded proteins: deposition, propagation and cure

My long-term goal is to understand the mechanisms that govern the deposition of misfolding-prone proteins, why they persist in aged cells and to identify strategies that could reduce the burden of misfolded proteins for cells and organisms. My work focuses on fundamental cell biological processes with the view that some of our discoveries will benefit human health.

Keywords: Protein misfolding / protein quality control / stress responses / protein aggregation / protein phosphatase / neurodegenerative diseases

Subject area(s): Molecular Medicine | Neuroscience | Proteins & Biochemistry