Biochemical and chemical approaches to biomolecular networks
Our group has pioneered biochemical methods, coupled to quantitative mass-spectrometry, with the aim of systematically linking dynamic protein interaction networks to various phenotypes in model organisms, human cells and human pathogens. We aim to advance network biology and medicine through the integration of quantitative biochemistry, proteomics and structural biology, and define system-wide hypotheses explaining complex phenotypes and human diseases.
Keywords
Systems biology / biomolecular networks / proteomes / protein complexes / lipidome