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EMBO Associate Member

Anne-Claude Gingras

Lunenfeld-Tanenbaum Research Institute, Toronto | Canada

EMBO 2020

Functional proteomics of signal transduction

My group develops and applies experimental and computational proteomics approaches for the discovery of protein-protein interactions and subcellular organization in vertebrates. We primarily focus on modulations of intracellular signalling pathways that are causative of cancer and other human diseases, notably the Hippo and mTOR pathways in cancer and the Cerebral Cavernous Malformation (CCM) pathway underlying a rare vascular disorder.

Keywords: Proteomics / interaction proteomics / signal transduction / phosphatases / mass spectrometry

Subject area(s): Systems Biology | Structural Biology & Biophysics | Proteins & Biochemistry