Guidance of vascular patterning
My laboratory studies vascular and lymphatic development, with particular interests in mechanisms that direct patterning and guidance. Specialized endothelial cells (EC) called tip cells located at the extremities of growing capillary sprouts mediate guided vascular patterning. Our research is focused on tip cell formation and guidance of angiogenesis and lymphangiogenesis.
Keywords
Endothelial cell / migration / vascular endothelial growth factor / axon guidance cues / mouse