EMBO Member
MPI für molekulare Zellbiologie und Genetik, Dresden | Germany
EMBO 2023
Our group investigates the impact of the cellular and organ architecture on the cells' fate choices and how single cells act in a community to generate an organ. To do so, we use mouse genetics and live imaging in 3D, and we developed 3D in-vitro 'organoid' culture systems modelling mouse and human development. These systems also enable us to gain insight into human syndromes impairing pancreas development.
Keywords: Developmental biology / stem cells / pancreas / organoids / endocrine / diabetes / differentiation / epithelial tubes
Subject area(s): Cell & Tissue Architecture | Development | Differentiation & Death | Molecular Medicine