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EMBO Member

Anne Simonsen

Institute for Cancer Research, Oslo | Norway

EMBO 2020

Molecular mechanisms of selective autophagy

The main focus of my lab is to characterize of the molecular mechanisms involved in cargo sequestration and autophagosome biogenesis during non-selective and selective types of autophagy, with a long-term goal to identify novel targets for diagnosis or treatment of human disease. To address these challenges, we use advanced imaging, genomic and computational approaches, as well as disease-related model systems.

Keywords: Autophagy / membrane traffic / mitochondria / endosome / phosphoinositide

Subject area(s): Membranes & Transport | Molecular Medicine | Proteins & Biochemistry