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EMBO Member

Antoine Triller

Institut de Biologie de l'Ecole Normale Supérieure (IBENS), Paris | France

EMBO 2012 | FelC 14–15

Biology of the synapse: from molecule to function

Studying normal and pathological synaptic biology, my objectives are: 1) to determine the relationship between the synapse microstructure, molecular dynamics, and molecular interactions; 2) to characterize the molecular mechanisms contributing to the physiological adaptation of inhibition to excitation; 3) to understand how non-neuronal glial cells modulate inhibitory receptor diffusion-trapping and ultimately impact on neuronal excitability.

Keywords: Synapse / receptors / molecular & dynamic organization / neuronal integration / super-resolution microscopy

Subject area(s): Neuroscience | Signal Transduction | Structural Biology & Biophysics