Netherlands Cancer Institute, Amsterdam | Netherlands
EMBO 1989 | Council 05–07 | Council 08–10 | Secretary General 10–12
My group focuses of genetically engineered mouse models for lung cancer and mesothelioma's. Major interest in this area is cell of origin of the different tumor subtypes and the spectrum of mutations that can drive tumorigenesis and could serve as targets for intervention.
Keywords: Proviral insertional mutagenesis / mouse models for cancer / transgenic & knockout technologies / tumor suppressor genes / oncogenes / gene therapy