Search    Show all

1 People found

filters applied:


1 / 1

EMBO Member

Antonella Viola

Università di Padova | Italy

EMBO 2016

Immune cell signaling

Spatiotemporal segregation of signaling molecules has a key role in activating specific downstream responses, and this is achieved by generating dynamic microdomains that protect and amplify receptor signalling. The assembly of signaling microdomains requires the interplay of membrane receptors, cytoskeletal proteins, plasma membrane lipids and subcellular organelles. We study signaling compartmentalization and amplification in immune cells.

Keywords: Leukocyte activation / cell polarity / signaling compartmentalization / inflammation / chemotaxis

Subject area(s): Immunology | Molecular Medicine | Signal Transduction