Search    Show all

1 People found

filters applied:


1 / 1

EMBO Global Investigator

Aravind Penmatsa

Indian Institute of Science, Bangalore | India

GIN 2021–2025

Mechanistic insights into ion-coupled transport

My laboratory is involved in understanding the mechanisms and pharmacology of transport processes across eukaryotic and prokaryotic cell membranes. We focus on exploring the architecture of neurotransmitter transporters and multi-drug efflux transporters to devise strategies to block their activity for therapeutic outcomes. This allows us to study the roles of transporters in disorders like chronic pain, epilepsy and multi-drug resistance.

Keywords: Neurotransmitter transporters / multi-drug efflux / ion-coupled transport / camelid antibodies / neuropharmacology

Subject area(s): Membranes & Transport | Neuroscience | Proteins & Biochemistry | Structural Biology & Biophysics