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EMBO Member

Arne Klungland

University of Oslo | Norway

EMBO 2025

Dynamic gene regulation in embryo development

Recent research has unraveled a remarkable diversity of modifications that adjust the coding properties of bases in DNA and RNA and amino acids of proteins. Such modifications are often dynamic, providing a reversible gene-regulation mechanism. Our aim is to identify writers, readers and erasers of such marks and to gain mechanistic understanding of their biological relevance with a focus on preimplantation embryo development.

Keywords: RNA modifications / epitranscriptomics / epigenetics / DNA damage / DNA repair / embryology / cancer

Subject area(s): Chromatin & Transcription | Development | Genome Stability & Dynamics

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