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EMBO Associate Member

Arthur Weiss

Max Planck Institute of Molecular Cell Biology and Genetics | United States

EMBO 2017

Signal transduction in lymphocytes

Our lab focuses on understanding T cell antigen receptor signaling, specifically how it regulates tyrosine phosphorylation. Recently, we have extended our studies to other cells of the immune system (macrophages, neutrophils, and B cells), with a focus on understanding the similarities as well as the differences in the signaling pathways that use the immunoreceptor tyrosine-based activation motif (ITAM).

Keywords: T-cell antigen receptor / ZAP-70 kinase / signal transduction / tyrosine phosphatase / lymphocyte development and activation

Subject area(s): Immunology | Proteins & Biochemistry | Signal Transduction