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EMBO Member

Asifa Akhtar

MPI für Immunbiologie und Epigenetik, Freiburg | Germany

EMBO 2013 | CouC 19–22

Epigenetic regulation of the X chromosome in flies

The major goal of our group is to study the chromatin and epigenetic mechanisms underlying gene regulation using dosage compensation as a model system. Dosage compensation in Drosophila is a powerful model system to study chromatin and transcription regulation at individual gene level as well from a chromosomal perspective. In order to achieve that we are employing biochemical, genetic, genomic and structural methodologies.

Keywords: Epigenetics / X chromosome / nuclear organization & dynamics / Drosophila / functional genomics

Subject area(s): Chromatin & Transcription | Proteins & Biochemistry | RNA