EMBO Young Investigator
Axel Innis
YIP 2018
Institut Européen de Chimie et Biologie (IECB), Pessac, France
How nascent and free peptides regulate translation
My group uses combined biochemical, structural and computational approaches to study some of the key events that take place within the functional nano-environment of the ribosomal exit tunnel. This includes translational arrest induced by nascent polypeptides known as arrest peptides, and bacterial ribosome inhibition by antimicrobial peptides or antibiotics.
Keywords
Ribosome / arrest peptides / protein synthesis / translation / antibiotics / antimicrobial peptides / gene regulation / metabolite sensing