MRC Centre for Developmental Neurobiology, London | United Kingdom
In our daily life, animal behaviour relies in a very precise connectivity between neurons in the brain that can be modulated by experience. In the mammalian cortex these connections reach an extraordinary complexity. How are these cortical circuits built? How they respond to activity and what happens when they fail during development causing neurodevelopmental disorders are questions that we are currently addressing in the lab.
Keywords: Cerebral cortex / synapses / interneuron / inhibition / development
Subject area(s): Neuroscience | Molecular Medicine | Development | Chromatin & Transcription | Cell & Tissue Architecture | Neuroscience | Molecular Medicine | Development | Chromatin & Transcription | Cell & Tissue Architecture