University of York | United Kingdom
We are studying the way in which insect flight muscle is activated by stretching. Flight muscle contracts at high frequencies when stretched periodically in a priming level of calcium. Contractions are regulated by troponin and we hope to find out how troponin responds to stretch as well as calcium. We also work on the elastic proteins in flight muscle. These determine passive tension and have a signalling function during development.
Keywords: Contractile proteins / insect flight muscle / cytoskeleton / muscle regulation / muscle development
Subject area(s): Development | Proteins & Biochemistry | Structural Biology & Biophysics