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EMBO Young Investigator

Benjamin D. Engel

Biozentrum, Basel | Switzerland

YIP 2021–2025

Cellular structural biology

My group is broadly interested in all forms of cellular organization, from membrane-bound organelles to cytoskeletal assemblies and phase-separated compartments. We ask how organelle architecture directs molecular function and, reciprocally, how macromolecules sculpt and shape organelles. To investigate these questions, we use cryo-electron tomography to directly visualize macromolecules 'in situ', within the native cellular environment.

Keywords: Cryo-electron tomography / cryo-EM / visual proteomics / membrane architecture / phase separation / photosynthesis / carbon fixation / cilia

Subject area(s): Cell & Tissue Architecture | Plant Biology | Structural Biology & Biophysics