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EMBO Member

Bertrand Séraphin

IGBMC, Illkirch | France

EMBO 2000

Eukaryotic mRNA decay

Our goal is to understand how the RNA decay process contributes both to regulated gene expression and to the elimination of defective transcripts. For this purpose my group characterizes protein complexes implicated in RNA decay and study their dynamic interactions. Using integrated approaches, we also analyze the connection of mRNA decay to other cellular processes to decipher globally the contribution of mRNA decay to gene expression control.

Keywords: mRNA turnover / protein complexes / proteomics / Saccharomyces cerevisiae / RNA splicing

Subject area(s): Microbiology, Virology & Pathogens | Proteins & Biochemistry | RNA