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Portrait of Bożena Kamińska-Kaczmarek

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Bożena Kamińska-Kaczmarek

EMBO 2022

Nencki Institute of Experimental Biology, Warsaw, Poland

Tumor microenvironment at single-cell resolution

We explore the role of tumor genetic heterogeneity in shaping microenvironment and reciprocal tumor-immune interactions in tumor progression and responses to therapeutic intervention. We interrogate TME using single-cell omics, immune phenotyping, 3D co-cultures, mouse models of brain tumors, multi-modal in vivo imaging. We attempt to find tumor vulnerabilities and develop targeted therapies interrupting tumor-microenvironment interactions.

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Brain tumors / tumor microenvironment / single-cell omics / antitumor immunity / transcription regulation / epigenetic memory / immunotherapy

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ORCID profile ↗Bożena Kamińska-Kaczmarek on EMBO’s Science Map