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EMBO Global Investigator

Brandon I. Morinaka

National University (NUS), Singapore | Singapore

GIN 2022–2025

Bacterial peptide natural products

Our group studies the biosynthesis and production of natural products from ribosomally synthesized and posttranslationally modified peptide (RiPP) pathways. We use a combination of genomic enzymology, synthetic biology, and analytical chemistry to identify and characterize unique posttranslational modifying enzymes. The resulting peptide products mediate microbial interactions and represent next-generation therapeutics for infectious diseases.

Keywords: Natural products / biosynthesis / peptides / posttranslational modifications / ribosomal

Subject area(s): Genomic & Computational Biology | Microbiology, Virology & Pathogens | Molecular Medicine | Proteins & Biochemistry