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EMBO Member

Brigitte M. Jockusch

Technische Universit├Ąt, Braunschweig | Germany

EMBO 1983

Actin complexes in cell adhesion and the nucleus

My research focusses on the interplay between actin and actin binding proteins, primarily in two cellular locations: (a) the adhesion aggregates of mammalian tissue forming cells engaged in cell motility, cell-cell and cell-substratum contacts, and (b) actin and partners residing in the eukaryotic nucleus. We generate motif-specific monoclonal antibodies and combine molecular and cell biology with biochemistry and immunocytochemistry.

Keywords: Actin binding proteins / cell adhesion complexes / microfilament system / nuclear actin / profilins

Subject area(s): Cell & Tissue Architecture | Proteins & Biochemistry | Signal Transduction