EMBO Associate Member
Bruce Beutler
EMBO 2009
University of Texas Southwestern Medical Center, Dallas, United States
We investigate the immune response, and other biological phenomena, using random germline mutagenesis. Toward this end, we have worked to develop methods for high speed positional cloning in mammals. These methods allow simultaneous detection of phenotype and assignment of mutational cause.
Keywords
Mutagenesis / innate immunity / mouse / inflammation / Toll-like receptors