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EMBO Member

Bruno Antonny

Institut de Pharmacologie Mol├ęculaire et Cellulaire (IPMC), Valbonne | France

EMBO 2008

Dynamics of lipid membranes and protein coats

Proteins from the cytosol continuously remodel the membranes of cellular organelles. Coats deform membranes into transport vesicles. Golgins, sort of molecular strings, tether vesicles to restrict their diffusion. Last, lipid-modifying enzymes induce changes in membrane composition. We study these mechanisms using molecular, cellular and in-silico approaches and focus on the effects of membrane curvature and composition (e.g. poly-unsaturation).

Keywords: Membrane traffic / small G proteins / protein coats / membrane curvature / self organization

Subject area(s): Membranes & Transport | Proteins & Biochemistry