EMBO Member
Bruno Antonny
EMBO 2008
Former EMBO Young Investigator (2002)
Institut de Pharmacologie Moléculaire et Cellulaire (IPMC), Valbonne, France
Dynamics of lipid membranes and protein coats
Proteins from the cytosol continuously remodel the membranes of cellular organelles. Coats deform membranes into transport vesicles. Golgins, sort of molecular strings, tether vesicles to restrict their diffusion. Last, lipid-modifying enzymes induce changes in membrane composition. We study these mechanisms using molecular, cellular and in-silico approaches and focus on the effects of membrane curvature and composition (e.g. poly-unsaturation).
Keywords
Membrane traffic / small G proteins / protein coats / membrane curvature / self organization