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EMBO Member

Caetano Reis e Sousa

Francis Crick Institute, London | United Kingdom

EMBO 2006

Link between innate and adaptive immunity

My group studies innate immune receptors and signalling pathways that trigger dendritic cell (DC) activation and promote T cell priming or that generally act to modulate the function of DC and other cells in response to changes in homeostasis. In a related research programme, the laboratory studies DC heterogeneity and ontogeny with a view to understand the role of distinct DC subtypes in mouse and in human.

Keywords: Innate immunity / dendritic cells / T cells

Subject area(s): Immunology